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Research line 1

RL 1: Analysis of existing and emerging biomarkers in individualised CVD risk assessment


The overall goal of this Research Line is to develop the stroke component of EPIC-CVD providing the foundation for subsequent work studying individualised CVD assessment.


Research Line specific objectives:


to verify diagnoses of incident stroke in suspected cases;


to retrieve and prepare samples from the EPIC central store for identified stroke cases;


to assess the impact of 22 clinical chemistry biomarkers on risk of incident CVD


to coordinate the activities for designing the analysis of data collected in the EPIC-CVD project;


to supervise the preparation of analytical plans for the main analyses related to soluble biomarkers (WP3, RL2, RL3) and hereditary markers (WP10, WP11); and


to supervise the preparation of analytical plans for risk assessment.